A hierarchical Bayesian model for comparing transcriptomes at the individual transcript isoform level
نویسندگان
چکیده
منابع مشابه
A hierarchical Bayesian model for comparing transcriptomes at the individual transcript isoform level
The complexity of mammalian transcriptomes is compounded by alternative splicing which allows one gene to produce multiple transcript isoforms. However, transcriptome comparison has been limited to differential analysis at the gene level instead of the individual transcript isoform level. High-throughput sequencing technologies and high-resolution tiling arrays provide an unprecedented opportun...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2009
ISSN: 1362-4962,0305-1048
DOI: 10.1093/nar/gkp282